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Pharmaceuticals News
December 12, 2019

Top Headlines
 

In mouse models of Alzheimer's disease, the investigational drug candidates known as CMS121 and J147 improve memory and slow the degeneration of brain cells. Now, researchers ... read more

Fruit Flies Live Longer With Combination Drug Treatment

A triple drug combination has been used to extend the lifespan of fruit flies by 48 percent in a new ... read more

New Way to Test for Drug Resistant Infections

Scientists have modified an antibiotic from the beta-lactam family so that it can be attached to a sensor, enabling them to detect the presence of bacteria resistant to ... read more

Scientists Can Now Manipulate Brain Cells Using Smartphone

A team of scientists have invented a device that can control neural circuits using a tiny brain implant controlled by a smartphone. The device could speed up efforts to uncover brain diseases such as ... read more
Latest Headlines
updated 10:15am EST

Earlier Headlines
 

Regional Trends in Overdose Deaths Reveal Multiple Opioid Epidemics

The United States in the grip of several simultaneously occurring opioid epidemics, rather than just a single crisis. The epidemics came to light after the researchers analyzed county-level data on ... read more

Co-Addiction of Meth and Opioids Hinders Treatment

A new study found that methamphetamine use was associated with more than twice the risk for dropping out of treatment for opioid-use ... read more

Current Treatment for Fungal Meningitis Is Fueling Drug Resistance

A common first-line treatment approach for cryptococcal meningitis in low-income countries is being compromised by the emergence of drug resistance, new research warns. The findings highlight the ... read more

Newly Engineered Peptide Shows Potential as Long-Acting Anti-HIV Drug

A newly engineered peptide called IBP-CP24 has the potential to be further developed as a long-acting anti-HIV drug that can be used alone or in combination with a broad neutralizing antibody for the ... read more

New Treatment for Brain Tumors Uses Electrospun Fiber

Researchers have developed a new treatment for glioblastoma multiforme, an aggressive form of brain ... read more

New Strategies Against Bone Metastases from Prostate Cancer

A study suggests a new approach, or, possibly two new approaches against prostate cancer bone metastases: While targeted therapies and anti-cancer immunotherapies have not been especially successful ... read more

Researchers Finally Grasp the Work Week of Enzymes

Scientists have found a novel way of monitoring individual enzymes as they chomp through fat. The method offers far greater insight into how enzymes function and opens up the possibility of tailoring ... read more

Hydromethylthionine Could Slow Cognitive Decline: Minimum Dose

Researchers have reported unexpected results of a pharmacokinetic analysis of the relationship between treatment dose, blood levels and pharmacological activity of the drug hydromethylthionine on the ... read more

New Flu Drug Drives Drug Resistance in Influenza Viruses

University of Wisconsin-Madison researchers examined the effects of baloxavir treatment on influenza virus samples collected from patients before and after ... read more

How an AI Solution Can Design New Tuberculosis Drug Regimens

With a shortage of new tuberculosis drugs in the pipeline, a software tool can predict how current drugs--including unlikely candidates -- can be combined in new ways to create more effective ... read more

Fighting Opioids With an Unlikely Supplemental Painkiller: Anti-Itch Medicine

Researchers are investigating whether an anti-itch medication that targets a specific part of our nerve cells can make morphine -- which targets a different part--more effective. The findings suggest ... read more

Investigational Drug for People With Treatment-Resistant Epilepsy

Imagine not being able to drive, shower alone or even work because you are never quite sure when the next seizure will leave you incapacitated. Hope may be on the horizon for epilepsy patients who ... read more

Directional Control of Self-Propelled Protocells

Synthetic protocells can be made to move toward and away from chemical signals, an important step for the development of new drug-delivery systems that could target specific locations in the ... read more

Experimental Cholesterol-Lowering Drug Effective at Lowering Bad Cholesterol, Study Shows

Twice-yearly injections of an experimental cholesterol-lowering drug, inclisiran, were effective at reducing low-density lipoprotein (LDL) cholesterol, often called bad cholesterol, in patients ... read more

New Clinical Guideline for the Treatment and Prevention of Drug-Resistant Tuberculosis

Researchers have published an official clinical guideline on the treatment of drug-resistant tuberculosis ... read more

Side Effects Mild, Brief With Single Antidepressant Dose of Intravenous Ketamine

Researchers found that a single, low-dose ketamine infusion was relatively free of side effects for patients with treatment-resistant depression. Widespread off-label use of intravenous ... read more

How Fibrosis Progresses in the Human Lung

A study boosts scientific understanding of how the lung disease idiopathic pulmonary fibrosis (IPF) progresses, providing a roadmap for researchers to discover new treatment targets for the ... read more

A Step Closer to Cancer Precision Medicine

Researchers have developed a computational model, Combined Essentiality Scoring (CES), that enables accurate identification of essential genes in cancer cells for development of anti-cancer ... read more

Blocking a Survival Mechanism Could Tackle Melanoma Treatment Resistance

The effectiveness of current treatments for melanoma, the deadliest form of skin cancer, could be improved by using approaches that wipe out the 'survival system' of cancer cells according ... read more

Diet Trials Often Amend Their Outcome Measures as They Go

A study concludes that 86 percent of diet trials amended their desired study outcomes along the way. That raises the possibility of ... read more

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